临床研究新突破！韩国顶级医院证实润迈德caIMR可精准预测...

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近期，韩国顶级医院三星医疗中心Joo Myung Lee教授团队发表研究文章 《STEMI术后基于造影的微循环阻力指数与心脏磁共振测量的微血管梗阻的一致性研究》，证实润迈德caIMR能够精准预测ST段抬高型心肌梗死（STEMI）患者PCI术后微血管阻塞，为患者带来更高的预后评估价值。对比心脏核磁共振技术（CMR），润迈德caIMR可在术后实时精准测量微血管阻力，并且评估微血管功能障碍，并具备比心脏核磁更好的临床适用性。作为全球首个进入确证性临床试验的非介入IMR测量产品，润迈德caIMR未来或将成为检验微血管阻塞的创新功能学金标准，迎接极具潜力的百亿蓝海市场。既往系列临床研究已证实，润迈德caIMR与导丝IMR具有高度一致性，并解决了传统基于介入导丝微循环测量方式的种种缺点，具备安全、高效、精准、简便、首创等优势，且caIMR能够准确预测ST段抬高型心肌梗死（STEMI）患者的PCI术后的远期不良心血管事件风险。前期的这些相关研究已经在《JACC》等顶级学术期刊发布，本研究进一步探索和研究了润迈德caIMR对STEMI患者急诊PCI术后微血管阻塞的诊断性能，并获得令人振奋的研究结果。这篇研究文章刊登在SCI期刊《Rev Esp Cardiol》上。研究表明，尽管STEMI患者可通过粉笔行政执法类申论百度网盘冠脉介入手术恢复心外膜血流，但高达三分之二的患者会因出现冠状动脉微循环功能障碍和微血管阻塞，而导致心肌再灌注损伤。因此，在PCI术后检测微循环功能障碍和微血管阻塞，能够有效评估患者血流恢复情况，发现潜在的治疗需求。心脏磁共振成像技术能够直观地观察和量化微血管阻塞情况，之前被认为是评估微血管阻塞的金标准。然而，在临床实践中，能获得心脏磁共振检查的STEMI 患者非常有限，且急诊PCI与心脏磁共振之间的时间间隔，使其无法及时在术后提供辅助诊断，因此临床作用十分有限。在这种情况下，IMR检测技术应运而生。此次研究对285名接受急诊PCI的STEMI患者分别进行caIMR和心脏磁共振检测分析，结果显示：1、润迈德caIMR能够独立预测心肌梗死患者急诊PCI术后，是否发生微血管阻塞现象，并且其判别能力显著高于TIMI血流分级、心肌呈色等级等传统评估指标。这一发现使润迈德caIMR有望成为临床微血管阻塞的主流检测手段。


预测CMR定义的微血管阻塞的鉴别能力比较（Angio-IMR项即为caIMR结果）

2、润迈德caIMR能够准确评估STEMI患者术后微血管阻塞情况。具体表现为，当caIMR＞40时，出现微血管阻塞比例更高，患者梗死面积、微血管阻塞范围和危险面积也更大，反之亦然。值得一提公务员体检听力测试的是，在6个月的随访超声心动图检查中，当caIMR＜40时，患者具有更好的心肌运动功能；当caIMR＞40时，患者的心肌运动功能较差。该发现进一步证实，润迈德caIMR对接受PCI治疗的心梗患者具有重要的预后指导价值。


caIMR和CMR参数之间的相关性（Angio-IMR项即为caIMR结果）

本次临床研究进一步揭示润迈德caIMR在临床实践中的适用性、重要性，及显著的预后价值。当前，润迈德caIMR临床研究持续传来好消息，相信随着临床探索的不断深入，caIMR必将拓展更加丰富的应用场景，为更多复杂的血管疾病带来全新的诊疗手段。润迈德医疗在前期推出了全球领先的冠脉供血能力精准检测产品caFFR。随着caIMR的即将上市和在临床中的大规模推广，心血管领域必将迎来全面综合评估心肌缺血的崭新时代。此外，润迈德caIMR与润迈德caFFR将作为功能学诊断模块核心系统，集成在公司研发推出的血管介入手术机器人上，辅助术者精准高效地完成术前诊断、术中指导、术后评估等全流程诊疗工作，助力解决医疗水平差异化、医患分布不均等诸多问题，推动健康中国建设，服务万众健康！文章来源： https://pubmed.ncbi.nlm.nih.gov/35249841/ (责任编辑：张远翔_NJ6638)政审考察领导同事说坏话

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